Management Outcome of Diabetic Keto Acidosis and Associated Factors among Adult Patients Admitted in the Emergency room of ST. Peter Specialized Hospital, Addis Ababa, Ethiopia, 2022

Background Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus, which is the major cause of death and disability globally. It was responsible for up to 73% of mortality in the first decade of diabetes. Despite the fact that diabetic ketoacidosis is recognized as a major health concern in developing countries like Ethiopia, there is very little data available about diabetic ketoacidosis management outcomes among adult patients in our country. Objective To assess the management outcome of diabetic ketoacidosis and associated factors among adult patients admitted in the emergency room of St. Peter specialized hospital, Addis Ababa, Ethiopia, 2022. Methods An institutional based cross-sectional study was conducted from April 18, 2022 to May 18, 2022 in the emergency room of St. Peter specialized hospital. A systematic random sampling technique was used to select the sample size of 245. The data was collected using a checklist through Open Data Kit (ODK) version 2022.1.2 software and analyzed by using SPSS version 26. To check the association between variables, binary logistic regression was performed. Finally, results were presented by using texts, tables, and graphs. Result This study included a total of 232 participants, with a response rate of 94.7%. From this, 81.9% had a good management outcome, while 18.1% had a poor management outcome. Having one or more comorbidities (AOR = 10.474, 95% CI; 3.235–33.91), Recurrence of DKA (AOR = 6.084, 95% CI; 3.23–33.91), and Failure to provide Potassium replacement therapy (AOR = 4.874, 95% CI; 1.683–14.113) were significantly association with poor DKA management outcome. Conclusion and recommendation : In this study, 18% of patients had poor management outcome. The presence of comorbidities, the frequency of DKA episodes, and the failure to provide potassium replacement were identified as associated factors for poor DKA management outcomes. Therefore, early detection and management of such factors are critical in order to reduce the risk of DKA poor management outcome. Clinical trial number: not applicable