Association of HbA1c with renal markers and lipid profile in Type 2 diabetic patients

The current study was conducted to determine the relationship between HbA1c and renal markers (urea, creatinine and uric acid and lipid profile (Total cholesterol, triglycerides, HDL, LDL and VLDL cholesterol ) in patients with type 2 diabetes. Participants in this control trial were to be between the ages of 35 and 45, regardless of gender. Three groups were formed out of them. Group 1 consisted of fifty healthy, normal people who had no family history of diabetes. Fifty patients with prediabetes were in group 2. 50 individuals with diabetes from the same population were part of Group 3. Participants in all three groups were asked to fast peripheral venous blood samples, which were then examined for serum uric acid, fasting blood sugar, renal markers, lipid profile and HbA1c levels. A direct relationship with blood sugar and HbA1c was observed with serum urea, creatinine,, uric acid ,cholesterol, TGL, HDL, LDL and VLDL. The measurement of HbA1c levels is important not only for monitoring of diabetes but also renal failure, gout and dyslipidemia associated with cardiovascular disease because some parameters were not significantly increased with increasing HbA1c level. Therefore, this study proves that even poor glycemic control (even if HbA1c levels go beyond 14.8%) between the age group 35 and 45 years old would not cause any severe complications but uncontrolled diabetes which exists more than ten years after crossing 50 years of old might cause severe complications like amputation, cataract, renal failure, gout and cardiovascular disease etc.