Invasive Ductal Carcinoma of Breast in 55-Years Old Male: A Rare Case Report from Pakistan

Background Breast cancer in a male is rare condition comprising less than 1% of all male cancers and breast cancers. Its incidence rate is less than 1 per 100,000 men, with a mean age of diagnosis at 67 years. Case presentation We present a case of 55-year-old normotensive and normoglycemic man with a four-months history of mild pain and lump in the left breast. Physical examination revealed a hard lump with overlying skin changes suggestive of malignancy. Incisional biopsies confirmed invasive ductal carcinoma, grade II with ER-positive, PR-negative and HER2/neu-negative status. Imaging studies showed lobulated mass in the left breast with axillary lymphadenopathy, renal calculus and benign lytic lesions. Initial treatment included Adrim and Cyclomide injections whilst residual invasive carcinoma remained persistent after nine weeks during follow-up. Thus, the patient was treated with second-line neoadjuvant therapy including Tab Tamoxifen with subsequent investigations indicating stability. The patient was stable and follow-up was advised. Conclusion This case highlights the unique aspects and challenges of diagnosing and treating male breast cancer emphasizing the importance of early diagnosis, hormone receptor status for treatment planing and ongoing research to manage male breast cancer effectively.