Preparation and characterization of electrospun PVA nanofibrous mat with Bryophyllum pinnatum for biomedical applications.

The present study represents the development of Nano mat from the mixer of PVA and Bryophyllum pinnatum ( B. pinnatum ) leaves extract that provides better performance as a biomedical material, especially in wound healing applications. After electrospinning, the mat underwent a series of analyses to determine its properties and structural composition. Scanning electron microscopy (SEM) was used to examine its morphological structure, revealing the detailed arrangement and surface features of the nanofibers. A moisture management tester (MMT) assessed the mat's ability to handle moisture, offering insights into its practical application potential. Fourier transform infrared (FTIR) spectroscopy was conducted to confirm the presence of chemical components derived from B. pinnatum within the nanofibers, ensuring the integration of the plant's properties into the material. These combined techniques provided a comprehensive evaluation of the mat's functional and structural attributes. Furthermore, the antibacterial performance of the nanofiber mat against Staphylococcus aureus ( S. aureus ) was studied. Result shows, the developed mat reveals an outstanding antibacterial property by forming a 10 mm inhibition zone against the abovementioned bacterial cells. MMT shows the rating of top wetting time, bottom wetting time and OMMC is good where top absorption rate is very good & bottom absorption rate is fair. The SEM analysis demonstrated the fiber formation having different diameter at a value of 174.45 nm along with a moderate level pore size distribution having 51.45% porosity and FTIR spectra analysis corroborate the availability of B. pinnatum components within PVA- B. pinnatum extract which is attributed to the better absorbing properties that could make it a promising wound healing material candidate.