Comparison of biometric measurements between swept-source OCT and OLCR devices in cataract patients: A prospective study

Purpose To compare the biometric measurements obtained from a swept-source optical coherence tomography (SS-OCT) device (Alcon ARGOS®) and an optical low-coherence reflectometry (OLCR) device (Topcon ALADDIN®) in cataract patients, and to evaluate the level of agreement and interchangeability between these two technologies. Methods This prospective, eye-based study included 100 eyes of 100 patients scheduled for cataract surgery. Axial length (AL), anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), flat and steep keratometry (K1, K2), mean keratometry (Km), and white-to-white (WTW) corneal diameter were measured using both devices. The sequence of device use was randomized. Paired-samples t-tests, intraclass correlation coefficients (ICC), and Bland–Altman analyses were performed to assess agreement. Results No significant differences were found between the devices for AL, ACD, LT, CCT, or keratometry values (p > 0.05). ICC values for these parameters were excellent (ICC > 0.98). WTW measurements, however, showed a statistically significant difference (p < 0.001), with ARGOS reporting smaller values than ALADDIN. The ICC for WTW was 0.82, and Bland–Altman analysis revealed broader limits of agreement for this parameter. Conclusion ARGOS and ALADDIN devices provide highly consistent and interchangeable measurements for AL, ACD, LT, CCT, and keratometry in cataract patients. However, WTW values should not be used interchangeably between these devices due to significant measurement bias.