Effect of Crush Syndrome Severity on Clinical Outcomes and Complications After the Earthquakes in Southeastern Türkiye

Background Crush syndrome is a potentially life-threatening complication of prolonged compression injuries, frequently encountered after earthquakes. The 2023 Kahramanmaraş earthquakes in Türkiye caused extensive crush-related trauma. The objective of this study was to assess the effect of baseline crush syndrome severity on hospitalization outcomes and complications. Methods In this multicentre, retrospective observational study, 962 crush syndrome patients hospitalized after the earthquakes were evaluated. Patients were grouped as mild-moderate vs. severe-critical based on clinical presentation. Demographics, laboratory results, comorbidities, trauma types, complications, and outcomes were assessed. Results Of 962 patients, 232 (24.1%) were classified as severe-critical and 730 (75.9%) as mild-moderate. Severe-critical patients had significantly higher rates of hypotension, ARDS, sepsis, DIC, arrhythmias, compartment syndrome, and ICU requirement (all p < 0.001). Laboratory markers including BUN, creatinine, potassium, phosphorus, liver enzymes, CK, and CRP were all significantly elevated, while calcium and albumin levels were lower in the severe-critical group (p < 0.05). Kaplan–Meier analysis revealed a significantly lower survival rate in the severe-critical group (67.7% vs. 97.7%, p < 0.001). Trauma types such as cranial, abdominal, and thoracic injuries were more frequent in this group, and prolonged entrapment time (median 24 vs. 11 hours, p = 0.031) was associated with increased severity. Conclusions Crush syndrome severity at admission is strongly associated with clinical outcomes, complication rates, and in-hospital survival. Prolonged time under the rubble, systemic complications, and elevated muscle and renal injury markers contribute to worse prognosis. These findings highlight the need for rapid triage, timely fluid resuscitation, and organized multidisciplinary intervention in future disaster scenarios.