Influencing Factors of Decentration and Tilt of Intraocular Lens with Extended Depth of Focus after Cataract Surgery

Purpose To analyze the preoperative biological measurement of extended depth of focus (EDOF) intraocular lens (IOL), explore the influencing factors of decentration and tilt. Methods Prospective, Follow-up clinical trial.156 age-related cataract patients (234 eyes) were selected. The EDOF IOL was implanted into the capsular bag. One month after surgery, the decentration and tilt of IOL were measured by OPD-SCAN III. Through univariate and multivariate linear regression analysis, the correlation between IOL decentration and tilt and preoperative ocular biological parameters (α angle,κ angle, axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and white to white (WTW) were evaluated. Results Univariate regression analysis showed that decentration was positively correlated with α angle, AL, ACD, LT, WTW; Horizontal decentration was positively correlated with horizontal α angle; Tilt was negatively correlated with AL, ACD, LT, WTW; Horizontal tilt was negatively correlated with horizontal α angle and horizontal nighttime κ angle. Multivariate regression analysis showed that decentration was positively correlated with α angle, AL, LT, WTW; Horizontal decentration was positively correlated with horizontal α angle and negatively correlated with horizontal daytime κ angle; Tilt was negatively correlated with AL and LT; Horizontal tilt was negatively correlated with horizontal α angle. Conclusion The larger the α angle, AL, LT and WTW, the larger the decentration of the IOL, while the smaller the AL and LT, the larger the tilt of the IOL. The greater the horizontal α angle, the greater the horizontal decentration and the smaller the horizontal tilt of the IOL.