Aspects of Pathogen Inactivation via Absorption of Short-Pulse UV- C Irradiation for Advanced Decontamination Strategies

The inactivation of pathogens using ultraviolet (UV) radiation has become a critical research focus following the COVID-19 pandemic, underscoring the need for advanced decontamination strategies against viruses, bacteria, and other pathogens. This study proposes the use of short pulses of UV-C radiation (220–280 nm) as an effective method for pathogen inactivation. Our primary objective is to evaluate the decontamination efficacy of pulsed UV-C radiation by varying the time intervals between pulses while maintaining constant pulse energy, and to analyze the resulting absorption spectra of a yeast solution across different irradiation durations. The research addresses two main components: (1) a theoretical model examining the effects of short UV-C pulses on biomolecules during radiation propagation, and (2) practical applications for pathogen diagnosis, treatment, and inactivation, with significant implications for ontogenetic and public health outcomes.