Relationship Between HbA1c Levels and Thickness of Carotis Intima Media in Prediabetic and Diabetic Patients

Objective: In this study, it was shown that cardiovascular risk can be reduced by controlling risk factors, and this can be achieved by measuring the carotid intima media (CIM) thickness and performing follow-up. An increase in atherosclerosis and cardiovascular risk factors is seen in the prediabetic stage, and CIM thickness measurement may help in preventing complications before developing diabetes and inflammatory processes. Study Design: Total 89 patients and 40 healthy controls were analyzed to determine the relationship between their mean HbA1c levels, laboratory data, and CIM thicknesses in patients with identified chronic diseases. Results: No significant correlation was noted between the mean HbA1c and right and left CIM thicknesses in patients with diabetes mellitus. In the prediabetic patient group, the a weak positive and signifiacant correlation was found between mean HbA1c and bilateral CIM thickness analysis. Conclusions: In conclusion, the risk of atherosclerosis and cardiovascular complications is increased in the prediabetic stage and non-invasive evaluation with treatment and follow-up may prevent complications, especially cardiovascular ones, in the diabetic stage.