Rare, Spesific, Systemic Organ Involvement in a Patient with a History of Oligoarthritis and Sjögren’s Syndrome: Case Report

Objective: Sjögren's syndrome is a chronic autoimmune disease characterized by involvement of exocrine glands and lymphocytic infiltrates. The presented case demonstrates the rare findings of systemic involvement in Sjögren’s syndrome. Case: A 45-year-old woman, diagnosed with Sjögren's syndrome in the rheumatology clinic, presented with mildly raised erythematous skin lesions, joint pain and intermittent cough. Physical examination arthralgia, polycyclic cutaneous lesions and bibasilar rales. Ultrasonography revealed parotitis, electromyography revealed peripheral nervous system involvement and high resolution tomography revealed lymphocytic interstitial pneumonia. Azathioprine and Rituximab 1000 mg on days 0 and 14 were started every 6 months. There was significant response in joint involvement, acute phase reactans and near complete response in signs of interstitial lung disease findings. Discussion: Considering that it is a systemic disease, clinical findings including nonspecific findings should be carefully evaluated and targeted treatment algorithms in systemic involvement should be organized specifically according to the organ involvement.