Modeling of the Body Surface Potential Map for Anisotropic Human Heart Activation

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Abstract

Modeling the bioelectricity of biological tissues, such the heart and brain, has been used in several studies and has been shown to produce results that are satisfactory when contrasted with actual data. The entire mathematical model of the challenge of creating a body surface potential map (BSPM) for the heart is presented in detail, from beginning to end. From the heart picture, a realistic Purkinje-network topology is used to generate the excitation propagation of the normal cardiac activation. Electromagnetic fields that can be detected as potential fields on the body surface and magnetic fields outside the body surface are produced by current sources that originate from potential differences between excitable and non-excitable tissues during cardiac tissue excitation. The finite element model for active tissues potential field equation has been developed by implementing a few boundary conditions and approximations that are appropriate for simulating biological tissues. With straightforward formulas, the formulation also accounts for the anisotropy of the cardiac tissues. A multi-pole anisotropic volume source operating in an inhomogeneous volume conductor is used to represent heart excitation. The ECG and Body-Surface-Potential-Map (BSPM) reference models have been used to validate the results.

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