Laboratory Evolution of Renal Donors: 10 Year Follow-up

Objective: evaluate the laboratory parameters of renal donors, identifying statistical markers of chronic kidney disease after kidney donation. Methods: statistical, retrospective study with patients at the kidney transplant outpatient clinic of the Centre for the Prevention of Kidney Diseases, Hospital Universitário - HUUFMA, for monitoring kidney donors. The collected data was analysed using the Shapiro-Wilk test, unpaired t test, Mann-Whitney and Pearson and Spearman correlations, in the computer program GraphPad. Results: The study included 50 kidney donors in healthy conditions, 68% of them female. Patients with CKD had an average microalbuminuria value of 57.8 with a standard deviation of 53.1, an average proteinuria of 176.9 with a standard deviation of 93.4, and an average uric acid of 5.64 with a standard deviation of 0.84, higher results than patients who did not have CKD. Conclusion: donors with renal dysfunction were more hypertensive (bp > 140 x 90) and had increased uric acid blood levels (UA>7,2). In addition, it was estimated that kidney donors were 10% more likely to have more positive CKD marker than the general population. Thus, there is a correlation between serum uric acid levels and a reduction in estimated glomerular filtration rate and an increase in microalbuminuria, consequences that may be more frequent in kidney donors.