Does being a night owl in migraine have any connection to higher migraine-related disability?

Background: Emerging evidence suggests circadian rhythms may influence migraine pathophysiology. This study investigates the association between chronotype and migraine-related disability. Methods: In this cross-sectional study, 200 migraine patients and 134 controls completed the Pittsburgh Sleep Quality Index (PSQI), Morningness-Eveningness Questionnaire (MEQ), and Migraine Disability Assessment Scale (MIDAS). Results: Migraine patients exhibited poorer sleep quality (PSQI: 7.28 vs. 4.37, p<0.001), with chronic migraine (CM) patients showing the highest disability (MIDAS: 36.17 vs. 9.63, p<0.001). No significant difference in chronotype distribution was observed between groups (p=0.48). Morning chronotypes had lower MIDAS scores (16.95±16.17) compared to intermediate (23.93±22.28) and evening types (23.55±20.85), though differences were non-significant (p=0.082). Conclusions: While chronotype does not directly correlate with migraine-related disability, poor sleep quality in migraine patients, particularly those with CM, underscores the need for sleep-focused interventions.