Model-Based Design of Experiments for adsorption isotherms

Designing adsorption processes requires knowledge of the adsorption isotherms. Measuring accurate isotherms is time consuming and inefficient equidistant points are usually chosen. Here, we combine isotherm measurements with Model-Based Design of Experiments to iteratively determine isotherm models with less experimental effort, while maintaining high model accuracy. Our joint approach combining isotherm model discrimination and parameter precision is validated by thermo-gravimetric experiments for the adsorption pairs Lewatit VP OC 1065 with CO2 and H2O and BAM-P109 with H2O, covering isotherm Types I, III, and V. Results show that the experimental effort couldbe reduced between 70 %–81 %. Furthermore, the framework scheduled measurements for Lewatit VP OC 1065/H2O to discriminate its isotherm Type between II or III, devoid of our bias as experimenters. Overall, our approach demonstrates potential to streamline the identification of adsorption isotherms while enabling more efficient and unbiased model development.