Ochrobactrum anthropi Urinary Tract Infection in an Immunocompetent Child: A Rare Case Report and Brief Review of the Literature
Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
Background Ochrobactrum anthropi , an opportunistic gram-negative pathogen, rarely causes urinary tract infections (UTIs), particularly in immunocompetent children. Only isolated case reports exist, with no consolidated clinical guidance. Case Presentation: A 6-year-old immunocompetent girl presented with fever (38.6°C), dysuria, and suprapubic tenderness. Pyuria (leukocyte esterase 3+, WBC > 50/hpf) and systemic inflammation (WBC: 23,840/mm³, CRP: 212 mg/dL) were noted. Urine culture grew O. anthropi (100,000 CFU/mL), resistant to ceftriaxone but sensitive to carbapenems. She achieved full recovery with intravenous meropenem. Literature Review: In our PubMed-based search, we identified only one previously reported pediatric case of O. anthropi urinary tract infection (UTI). To the best of our knowledge, this represents the second documented case of O. anthropi UTI in a pediatric patient. O. anthropi infections predominantly manifested as bacteremia, catheter-related bloodstream infections, sepsis, and septic shock in pediatric age group. Only five pediatric cases deviated from this pattern, highlighting the rarity of alternative infection types in children. Conclusion O. anthropi should be considered in pediatric UTIs unresponsive to empiric therapy, regardless of immune status. Early culture-guided treatment and thorough evaluation for immunodeficiency and/or underlying risk factors (e.g., posterior urethral valves, constipation, or other causes of urinary stasis) are critical to prevent complications.