Management of periodontitis by three different approaches to non-surgical periodontal debridement – A randamized comparative clinical study

Background Non-surgical periodontal therapy (NSPT) is the cornerstone of periodontitis management. This comparative clinical study evaluates the effectiveness of three different non-surgical treatment approaches in three treatment groups namely, Quadrant-wise Scaling and Root Surface Debridement (Q-Sc + RSD), Full-mouth Disinfection (FMDis) and Full-mouth Debridement (FMDeb). Methods A total of 45 patients with generalised periodontitis were randomly assigned to one of the three treatment groups. Plaque scores (PS), bleeding scores (BS) and probing pocket depths (PD) were recorded at baseline and post-NSPT. Data was analysed to compare the changes in BS and PD distribution at baseline and post-NSPT, in all three groups. Results All three treatment approaches resulted in statistically significant reductions in BS and PD distribution compared to baseline. However, FMDeb and FMDis protocols demonstrated greater reductions in BS and PD distribution compared to the Q-Sc + RSD protocol. Remarkably low BS were observed in all three study groups at the post-treatment evaluation, with statistically significant differences, compared to their respective pre-treatment BS. Conclusions All three treatment approaches were effective in reducing BS and PD in patients with periodontitis, while FMDeb and FMDis protocols demonstrated superior effectiveness in terms of reduction of BS and PD, compared to Q-Sc + RSD protocol. Further research with larger sample sizes and longer follow-up periods may be warranted to confirm these findings and evaluate the long-term clinical outcomes of these different debridement approaches of NSPT. Clinical Trial No: The UK’s Clinical Study Registry ISRCTN13350022, 28/05/2025, retrospectively registered