Engaging Vulnerable Populations Around mRNA Vaccines to Build Tailored Education and Improve Vaccine Confidence

Background Clinically and socially vulnerable populations are at an increased risk of hospitalization if they contract COVID-19. This paper aims to understand the perspectives of clinically and socially vulnerable populations across Canada in relation to COVID-19 vaccines. Methods This study employed qualitative semi-structured interviews (n = 13) with organizations who serve clinically and socially vulnerable people across Canada to understand their perceptions surrounding COVID-19 vaccines and the vaccine’s impact on clinically and socially vulnerable populations. Participants met the following criteria: 1) were over the age of 18, 2) spoke English, and 3) worked at an organization which serves either a clinically or vulnerable population. Interviews were voice recorded and transcribed before being thematically analyzed. The generated themes were translated into actionable information for the development of educational materials on vaccination for vulnerable communities. Results Findings from the interviews provided four major themes: 1) Vulnerable populations are keen to get vaccinated but the general public no longer sees the value of vaccination; 2) Clear and reliable information about vaccine eligibility is needed; 3) To increase vaccine uptake, misinformation related to mRNA vaccines needs to be addressed; and 4) Personal experiences and the experiences of family and friends inform perceptions of vaccines. Conclusion There is an apparent knowledge gap among vulnerable populations regarding COVID-19 vaccination safety, efficacy, and guidelines resulting in apprehensiveness towards receiving doses. The creation of educational materials that are tailored to community needs and informed by vulnerable group’s perspectives can effectively address barriers regarding vaccination and to further promote vaccination among these communities.