Report of radiological diagnosis and bioinformatics analysis of head and neck lymphoma

Malignant lymphomas that affect the head and neck region, including both Hodgkin's and non-Hodgkin's types, are serious cancers that pose significant challenges for early diagnosis. In our study, we employed bibliometric methods to analyze 5,253 scholarly articles from the Web of Science database, covering the years from 1978 to 2025, to better understand the current research landscape and future directions in this field. Our findings revealed that a substantial majority, specifically 68.91%, of these publications were produced in the last decade (2015-2025), indicating ongoing scientific interest in this area. Notable research institutions leading the way included Memorial Sloan Kettering Cancer Center, which published 95 articles, and Mayo Clinic with 85 articles. Among individual contributors, Albano D had 37 citations, while Meignan M stood out with 107 citations. Key journals that disseminated this research included well-established publications like Leukemia & Lymphoma, which featured 131 articles, as well as newer journals such as Cancers. Our term frequency analysis highlighted "prognostic factors" with 244 mentions and "positron emission tomography/computed tomography" with 225 mentions as the most frequently discussed concepts. Furthermore, the focus of contemporary research is shifting towards "radiomic analysis" and "metabolic tumor burden quantification." The integration of radiomic techniques with molecular signature profiling shows great potential for overcoming existing diagnostic challenges in this field.