Phytochemical Screening and Pharmacological Evaluation of Passiflora foetida L. Leaf Extract Found in the Vicinity of Lonar Lake: A Distinctive Saline Crater Lake in India

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Abstract

Lonar Lake Distinctive Saline Crater Lake Located in Maharashtra's Buldhana district, India, Crater Lake is encircled by thick woodlands containing numerous plants with medicinal properties. Passiflora foetida L. commonly known as stinking passion flower has been used as traditional medicine in treating diseases such as throat infection, giddiness, liver disorder, diarrhea, tumor, nervous disorder, anxiety, sleep disorders, skin infections, hysteria and asthma. The Ethyl acetate and ethanol extracts of Passiflora foetida L. leaves were subjected to GC-MS analysis. The Ethyl acetate extracts yielded thirty-four phytochemical compounds, while the ethanol extracts revealed twenty-eight phytochemical compounds upon analysis. The compounds were identified by comparing their retention time and peak area with that of the literature and by interpretation of mass spectra. Using the agar disc diffusion method antibacterial and antifungal properties were evaluated for extracts obtained using n-hexane, ethyl acetate, acetone, ethanol, methanol, and water as solvents.

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