Comparative analysis of the biomechanical properties of adult patients with high myopia after implantable collamer lens (ICL, V4) implantation

Background To evaluate the effects of ICL implantation on the corneal biomechanical parameters of patients with high myopia Methods Corneal biomechanical parameters were measured preoperatively and postoperatively in 110 eyes of 55 high myopia patients who underwent ICL implantation by the same surgeon between January 2021 and December 2022. Measurements were obtained using Pentacam, and Corvis ST. Results Comparative analysis of Pentacam parameters before and after ICL surgery revealed significant differences in Astig F and ISV at one week, one month, and three months postoperatively (P < 0.05). IVA showed significant differences only at the three-month mark compare to preoperative measure (P < 0.05). No significant changes were detected in other parameters (K1 F, K2 F, CCT, TP, KI, CKI, IHA, and IHD) across all time points (P > 0.05). In Corvis ST parameters, A1T, A1V, A2T, PD, HCDfmA, HCDflA, and DA Ratio showed significant changes at one week, one month, and three months postoperatively compare to preoperative measures (P < 0.05). Additionally, there were significant differences observed between one month and three months postoperative for A1T, A1V, A2T, A2V, PD, HCR, HCDfmA, HCDflA, SP-A1, IR, and DA Ratio (P < 0.05). A2V demonstrated a delayed response, showing significant changes only at later postoperative stages. Other parameters did not show significant changes postoperatively (P > 0.05). Conclusions ICL implantation significantly affects certain corneal biomechanical parameters, with both immediate and persistent changes observed following surgery