Novel Ca/Mg/ Chitosan Layered Double Hydroxide (LDHs) Modified with Hydroxyapatite as New Dental Nanocomposites; Mechanical and Antibacterial Study
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In this study we demonstrate an efficient and cost effective synthesis of novel Ca/Mg/Chitosan layered double hydroxides (LDHs) modified with hydroxyapatite. The chitosan as a biotemplate was extracted from whiteleg shrimp (Litopenaeus vannamei (shell. Modification and functionalization of the LDHs with chitosan structures can lead to new biotechnological and biomedical applications. Ca (NO 3 ) 2 .4H 2 O in this approach was applied as simultaneous precursor for synthesis of Ca/Mg/Chitosan LDHs and also Ca₁₀ (PO₄)₆(OH) ₂. The final nanocomposites were characterized extensively with scanning electron microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), Dynamic light scattering (DLS), Thermo-gravimetric analysis (TGA) and differential thermal analysis (DTA). The experimental results showed for the new nanocomposites mechanical properties such as the flexural strength, modulus and compressive strength at 0.1 mg H 2 PO 4 can be promoted to 198.0 MPa, 28.5 GPa and 198.0 MPa and also at 2 mg chitosan evaluated 210.0 MPa, 21.2 GPa and 211.0 MPa respectively. The antibacterial test demonstrated that this resin nanocomposite has minimal inhibitory concentration (MIC) about 2 < MIC ≤ 4 for gram-positive and gram-negative bacteria.
