The outcome of pre-renal transplant bladder cycling in patients with defunctionalized bladder

Purpose to evaluate the effectiveness of programmed bladder cycling (PBC) prior to transplantation in patients with defunctionalized bladders (DB). Methods Renal transplant (RT) patients with DB were included in this prospective cohort research. Pre-transplant PBC was given to eligible individuals, and urodynamic alterations before and after bladder cycling were compared. Evaluating PBC's effectiveness in increasing bladder capacity was the main goal. The evaluation of renal functioning, voiding parameters, and perioperative urological problems were the secondary outcomes. Results 23 patients underwent PBC for a maximum of 6 months duration. 20 (86%) patients achieved the targeted bladder capacity of 250 ml with the improvement of bladder capacity from (141.50 ± 17.48) to (266.75 ± 34.73) ml. There was a highly significant improvement in the bladder capacity after 3 and 6 months of RT from (313.40 ± 35.68) ml to (371.00 ± 41.46) ml, respectively. There was a highly statistically significant improvement of the urodynamic parameters pre- and post-PBC before RT with (P-value <0.001) bladder compliance from (12 ± 3.32) to (25.05 ± 6.55) mL/cmH2O. Fever and UTI that needed hospital readmission were reported in 3 (15%) patients. The renal function after 3 and 6 months post-RT showed significant improvement from (1.25 ± 0.21) to (1.14 ± 0.22) mg/dl with (P-value=0.033). Conclusion PBC is a simple outpatient maneuver that significantly increases bladder capacity and compliance in patients with DF and decreases complications that may occur during and after renal transplantation.