Clinical characterization of 145 cases of botulinum toxin injection-induced cosmetic poisoning

Botulinum toxin injection for cosmetic purposes can lead to poisoning, but the factors influencing the length of hospitalization in such cases remain to be clarified. A retrospective analysis was conducted on clinical data of 145 patients with botulinum toxin injection poisoning admitted to the Twelfth People's Hospital of Guangzhou City between June 2024 and February 2025. General data were statistically described, clinical data were analyzed using one-way analysis, and meaningful multifactorial indices were screened via the Cox regression model to construct a clinical prediction model for hospitalization duration. The study included 145 cosmetic botulinum toxin injection poisoning patients, predominantly female, with most injection doses ranging from 50–100 U and injection sites primarily on the head and face. Statistical analysis identified three key indicators significantly impacting hospitalization length: the number of days of antitoxin use, dysphagia, and slurred speech. A prediction model for hospitalization duration was constructed using a line graph based on these factors. The length of hospitalization for botulinum toxin poisoning is closely associated with antitoxin use duration, slurred speech, and dysphagia. The developed prediction model can serve as a reference for individualized estimation of hospitalization length in such patients at the hospital.