Serological Evidence of Likely Reactivation Recurrent or Reinfection in Sars Cov2 Infection

The ongoing COVID-19 pandemic continues to display varying dynamics in transmission, clinical manifestation, and recovery rates. In August 2020 asymptomatic male adult who was on transit reported to health authorities as been positive to COVID-19. He was evacuated to quarantine center, another test confirmed him positive, and his blood samples were obtained. Vital signs remain normal throughout isolation with no visible symptom, and he tested negative after 14 days. While still in quarantine facility, returned for another test 5 days after and he remained negative, 3 days after another sample was taken which came up positive. A confirmatory test was carried out the next day remained positive. He had low neutrophil, elevated S-ferritin level, and carbonate as well as IgG and IgM measuring a four-fold rise in titer. The reduction in neutrophil could be a reason for reactivation of the virus since the immune system may not have completely cleared the infection but the generality of the immune system was not compromised as indicated by high level of ferritin a sign of inflammatory response due to infection by the virus. It is recommended that a follow up of COVID-19 survivors may be necessary, though there is no evidence that they are transmitting the virus. Africa with paucity of research needs to document as much as possible new pathophysiological presentation of covid-19 to assist clinicians and scientists alike in making appropriate decisions.