Dynamic Alterations of Brain Activity Patterns revealed by Regional Homogeneity in Patients after Laser-assisted Subepithelial Keratomileusis Surgery: A Resting-State Functional MRI Study

  1. Hui Zhang
  2. Zhen-Zhe Liu
  3. Liang-Qi He
  4. Jin-Yu Hu
  5. Cheng Chen
  6. Hong Wei
  7. Qian Ling
  8. Yan-Mei Zeng
  9. Xiao-Yu Wang
  10. Xu Chen
  11. Yi-Xin Wang
  12. Yi Shao
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Abstract

Objective Previous studies have reported that myopia may lead to regional changes in brain activity. In this study, we aimed to investigate cerebral activity alteration by comparing pre-LASIK (PRL) and post-LASIK (POL) patients using the dynamic regional homogeneity (dReHo) technique. Methods 18 individuals with myopia (9 male and 9 female) all underwent resting-state functional magnetic resonance imaging (rs-fMRI) and completed the Hospital Anxiety and Depression Scale (HADS). These patients comprised both the

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  1. Version published to 10.21203/rs.3.rs-6420335/v1 on Research Square