Relevant Hemolysis Parameter associated with ARF and CRF Patients in Dialysis

Renal Failure (RF) patients undergoing hemodialysis and comparing them with studies period. This study aimed to determine the relevant hemolysis associated with Acute Renal Failure (ARF) and Chronic Renal Failure (CRF) patients in Centre of Dialysis and Renal Diseases in Hodiedah, Yemen. during the period years 2022. The study was designed in retrospective study ( cases series study) a set patient various stages of ARF and CRF who presented at the nephrology clinic and age and sex of patients of single value Concentrations of Creatinine, Hemoglobin (Hb), Mean Corpuscular Hemoglobin Concentration (MCHC), Hematocrit (HCT) and Hemolysis Parameters Use the Sysmex Hematological Analyzer for Assaying (CBC) and Spectrophotometers for Assaying Concentrations of Creatinine and Total Bilirubin. The study included 52 patients. The results showed That Relationships between the Observed Variables Relevant Hemolysis Parameter by Analyzer (CBC) association with Creatinine to ARF and CRF patients. The Mean of Age was 40 ± 20 years of patient with 75% of Males and 25% of Females. Mean Values of Serum Creatinine Significantly higher in the patients (8.15 ± 1.8 5 mg/dl). There was Significant Reduction in the Mean Values of Hb (7.55 ± 0.75 mg/dl ) and Values of HCT (25.3℅ ±2.5 ℅). The Mean Total Bilirubin was (13.95 ± 5.55 mg/dl) and Hemolysis (%) was (32.05 ± 12.65). and MCHC was 33.5 Stebal in these study. While the Mean of Age of ARF was 40 ± 20 years with 63.46% of Males, and 36.64% of Females. The Mean of Serum Creatinine Significantly higher in the patients (6.55 ± 4.15 mg/dl). There was significant lower in Hb Namely 8.95 ± 3.15 mg/dl and Values of HCT 29.9℅ ±10.5 ℅. The Mean of Total Bilirubin was 1.1 ± 0.9 mg/dl, Hemolysis 1.3 ℅ ± 0.88 ℅ and MCHC was 33.5 Stebal. ARF and CRF were higher Hemolysis Parameter that may result in either damage or lysis of the more fra gile populations of red blood cells (RBCs) because jaundice Disease and higher Creatinine, Blood Urea due to change in Osmolality in patients and filters Hemodialysis Devices play role .