HPD: a comprehensive database for clinically relevant human pathogens

Objective The increasing threat of infectious diseases necessitates robust genomic resources for rapid and accurate analysis of human pathogens. The Human Pathogen Database (HPD) addresses this need by providing a comprehensive, curated collection of pathogen data. The database was built on high-quality, manually organized data of human pathogens, offering an interactive interface for online browsing, searching, downloading, and sequence alignment of pathogen data. Results The current iteration of HPD encompassed approximately 16,000 entries of human pathogens, including more than 10,000 bacteria, more than 4,000 viruses, more than 1,000 fungi, and more than 400 parasites. These entries were interconnected with genomic sequences, disease data, and relevant literature, creating a powerful tool for researchers to conduct comprehensive pathogen studies. The HPD not only supports pathogen blasting, genome downloading, storing, and sharing but also provides a user-friendly platform. This platform enables effortless querying and exploration of its vast repository of information, making the HPD a go-to resource for scientists seeking to delve into the genomics of human pathogens with ease and efficiency.