Enhancing Diagnostic Accuracy and Management of Major Depressive Disorders via Tailored Musical Interventions and Neuro-acoustic Stimulation

Major Depressive Disorder (MDD) is a disabling and prevalent mental illness, usually diagnosed based on subjective clinical observations, which may compromise diagnostic accuracy and treatment delay, The current situation highlights the need for more accurate, objective, and innovative approaches. This study aims to explore the effectiveness of personalized musical interventions combined with Neuro-Acoustic Stimulation (NAS) and Neuro-Acoustic Loop Methodologies (NALM) in enhancing diagnostic accuracy and treatment protocols for MDD, carried out at the Kashmir Advanced Scientific Research Centre (KASRC), a DSIR-accredited institution, this research employs a mixed-methods approach. Participants diagnosed with MDD underwent tailored musical interventions designed to resonate with their specific emotional and cognitive needs. At the same time, NAS techniques were utilized to stimulate neural pathways associated with mood regulation. Preliminary outcomes reveal that the combination of personalized musical interventions with neuro-acoustic stimulation significantly enhances the accuracy of MDD diagnosis and treatment outcomes. Participants reported reductions in depressive symptoms and increased engagement in their treatment, suggesting that this multimodal and interdisciplinary approach not only enhances diagnostic accuracy but also suggests an innovative paradigm for preventative strategies and therapeutic interventions in mental health care.