A Comparative Examination of Omega-3 Fatty Acids in the Lactation Period with Cancer Stem Cell Biomarkers

This research was planned with the aim of making a comparative investigation of fish oil, flax seed oil and walnut oil, which are rich in omega-3 fatty acid and are taken to enrich the maternal diet during lactation with the biomarkers BRCA1 and CD44, which are cancer signal molecules in the breast tissue structure and the mammary glands. The rats were randomly divided into five groups: negative control, control, fish oil, flax seed oil and walnut oil groups. These oils were given by gavage to the rats. A significant difference was observed between the fish group, the walnut group and the negative control group in BRCA1 and CD44 in terms of both immunohistochemical and biochemical concentration (p<0.05). It was seen that fish oil suppressed the cancer stem cell signal molecules more in the breast tissues of the breastfeeding mother rats.