Exploring the Antimicrobial Potential of Ziziphus mauritiana: A study of its Various Parts

Ziziphus mauritiana , a tropical tree in the Rhamnaceae family, is recognized for its nutritional and medicinal benefits. This study examined the antimicrobial effects of its various parts—leaves, roots, bark, stems, and fruit—against Escherichia coli and Fusarium solani , using methanolic extracts tested at concentration of 1.0 mg/mL with the disc diffusion method. The bactericidal and fungicidal efficacy was confirmed at MBC/MFC values of 0.8 mg/mL for E. coli and 1.0 mg/mL for F. solani . Methanolic extracts displayed notable inhibition zones, with maximum inhibition for F. solani by leaves extracts at 88.11 mm² and root extracts reaching 86.48 mm². For E. coli , methanolic leaves extracts reached up to 101.47 mm². These results affirm the medicinal promise of Z. mauritiana extracts, particularly in methanolic forms, positioning it as a solvent for developing natural antimicrobial agents. The study supports Z. mauritiana 's potential in treating human diseases and underscores the need for sustainable conservation.