Metagenomic sequencing of microbial communities in midgut of Spodoptera frugiperda larva induced by Serratia marcescens WY 26

Background In recent years, the control effect of Serratia marcescens and its metabolic products on insects has attracted the attention of many scholars worldwide. This study investigates the potential of S. marcescens strain WY 26 as a biocontrol agent and its effect on the gut microbiome of Spodoptera frugiperda larvae. Result The metagenomic sequencing revealed significant changes in the gut bacterial community structure post-infection, with S. marcescens becoming the dominant species. The infection led to alterations in metabolic and immune response pathways within the gut, affecting the larval growth and metabolism of S. frugiperda . Field efficacy trials demonstrated the potential of WY 26 as a biocontrol agent, with enhanced and sustained efficacy when integrated with chemical pesticides. Conclusions The study provides insights into host-pathogen interactions and the role of the gut microbiome in insect health and disease resistance, offering a promising avenue for pest control strategies.