The Role Of S100B Calcium-Binding Protein And Some Biochemical Markers In Early Detection And Progression Of Breast Cancer

Breast carcinoma is the most typical malignancy among women. Therefore, early detection with breast cancer is helpful for the treatment, although other markers are required to increase accuracy. The study's objectives were to determine the effects of these markers on patients with breast cancer and the role that immunoglobulins (IgG, IgM) and S100B levels play in early diagnosis and the ability to distinguish between benign and malignant breast cancers. There were a significant increase in levels of IgG, IgM, calcium, ALP and S100B in breast cancer women in comparison with pathological and healthy controls. While there were no significantly differ in levels of IgG, IgM, and S100B, when compared pathological controls to healthy controls. These values of IgG, IgM, and S100B can be used in differentiation between benign tumors from malignant breast tumors .While a significant decrease in 1,25(OH)2 Vitamin D, phosphorus patients with breast cancer in comparison with healthy controls .These values make these parameters highly significant for early diagnosis and progression of breast cancer.