The Role of PR-5 Genes in Inducing Toxicity and Resistance in Potato Against Phytophthora infestans

The pathogenesis-related protein 5(PR-5) gene family plays a role in multiple biological processes within plants. To develop resistant potato varieties, it is crucial to understand the molecular defense mechanisms against Phytophthora infestans pathogen, particularly the pathogenesis-related (PR) gene family, specifically PR-5. In this study, we conducted a comprehensive analysis of the PR-5 gene family in potatoes at the genome-wide level and investigated their role during P. infestans infection by examining their expression patterns. By utilizing bioinformatics tools and high-throughput sequencing approaches, we successfully identified and confirmed the presence of the PR-5 gene family in the potato genome. Furthermore, phylogenetic analysis shed light on the evolutionary relationships among these genes, suggesting potential functional diversification. The RNA-seq data revealed increased expression of several PR-5 genes when the plants were infected with P. infestans , indicating their involvement in the plant's defense response against the pathogen. By identifying gene targets associated with late blight resistance, we have established a foundation for future research on plant-pathogen interactions and disease resistance in potatoes. This knowledge will facilitate the development of molecular breeding and genetic engineering strategies. Furtherore, our comprehensive genome-wide analysis and high-throughput expression profiling of the PR-5 gene family in potatoes have uncovered a novel mechanism for understanding plant defense at various levels. This research contributes to sustainable agriculture and the development of resistance to Phytophthora infestans in potatoes.