Prognostic Value of Nucleated Red Blood Cells in Patients with Acute Pancreatitis in the Emergency Department: A Single-Center Retrospective Study

Aim : In this study, we sought to investigate the success of nucleated red blood cells (NRBCs _{) in predicting disease severity and mortality in patients with AP. Methods: This single-center, retrospective study was conducted in AP patients admitted to the emergency department. NRBCs values and other laboratory data were recorded in the study form. Patients were divided into three groups according to disease severity (mild, moderate and severe) and two groups according to outcome (survivors and non-survivors). Results: Half of the 296 patients included in the study were male and the mean age was 55.6±17.9 years. NRBCs values were higher in severe cases than in mild and moderate groups. In the Receiver operating characteristic (ROC) analysis performed to determine disease severity, the specificity, sensitivity and area under curve (AUC) values for NRBCs were 58,8%, 91.8%, and 0.755, respectively. The NRBCs values were higher in non-survivors patients than in survivors patients. In the ROC analysis performed to detect non-survivors patients, the specificity sensitivity and AUC values for NRBCs were 63,6%, 90,9% and 0.770, respectively. Conclusion: In AP patients, high NRBCs levels may be successful in predicting both disease severity and mortality. However, more studies are needed for clinical use}