Papillary Thyroid Carcinoma Originated in Thyroglossal Duct Cyst: Case Report

Purpose : The Thyroglossal Duct Cyst (TDC) is the most prevalent congenital developmental anomaly in the neck, nevertheless, papillary carcinoma emerging from thyroglossal cyst (TGDC) represents an exceptional finding, and the associated appearance with Papillary Thyroid Carcinoma (PTC) is even more uncommon. The clinical presentation is usually almost identical from a benign lesion and the postoperative histopathological study defines the diagnosis. However, its surgical management and follow-up is still debatable because there is no standard consensus for this. The aim of this work is to describe a case of papillary thyroid carcinoma which arise in a histopathological confirmed thyroglossal duct cyst, associated with papillary thyroid carcinoma of different histological variant, an infrequent condition. Methods and Results: This is a case report of papillary thyroid carcinoma emerging from thyroglossal duct cyst, with clinical and imaging attribute of thyroglossal duct cyst, offering surgical management with Sistrunk Procedure (SP) with histopathological result of classical variant of PTC, with invasion to capsule wall. Cabinet tests in the absence of abnormal anatomical findings in thyroid gland, being considered an aspirant for total thyroidectomy (TT) in a second stage, with result of follicular variant of PTC. Conclusion: TGDC is unusual and is commonly detected after surgery. Due to its almost indistinguishable presentation from benign pathology, it constitutes a defiance for the surgeon, being SP the first therapeutic step, in some cases it is fulfill with TT and ablative therapy with radioiodine, nevertheless, there are no systematize recommendations concerning to the surgical therapeutic outcome and its follow-up.