Changing patterns of the burden for atrial fibrillation /atrial flutter attributable to high systolic blood pressure in China From 1990 to 2021

This study aims to investigate the changing patterns of the burden for atrial fibrillation (AF) /atrial flutter (AFL) attributed to high systolic blood pressure (SBP) in China. Data were sourced from the Global Burden of Disease (GBD) 2021 project. The disease burden of AF /AFL attributed to high SBP in China from 1990 to 2021 was analyzed stratified by sex and age, along with the trend prediction from 2022 to 2050. In China, between 1990 and 2021, the age-standardized mortality rate (ASMR) and the age-standardized disability-adjusted life years (DALYs) rate (ASDR) of AF/AFL attributable to high SBP in male have been increasing, and the trend will continue till 2050, whereas in female, the trend is slightly downward. Globally, however, the disease burden according to the estimated annual percentage changes (EAPC) of ASMR and ASDR presents a deducing trend in both genders between 1990 and 2021. The main driver of the increased DALY burden for AF /AFL attributed to high SBP is population aging. In China, the disease burden of AF/AFL attributable to high SBP in male has been increasing between 1990 and 2021 and keeps an upward trend till 2050, whereas in female, the trend is slightly downward. Our research implies that the public health decision-making needs to give sufficient attention to alleviate the burden of AF /AFL attributable to high SBP in China by promoting awareness, treatment, and controlling rates of hypertension, especially in male.