A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands

  1. Shihong Zhang
  2. Tzu-Hao Tang
  3. Sinéad Kinsella
  4. Francesco Mazziotta
  5. Michael T. Schweizer
  6. Megan S. McAfee
  7. Ariunaa Munkhbat
  8. Yapeng Su
  9. Valentin Voillet
  10. Lauren E. Martin
  11. Colton W. Smith
  12. Yuta Asano
  13. Menna Hailemariam
  14. Jakob Bakhtiari
  15. Bo Lee
  16. Cecilia Yeung
  17. Hung Chen
  18. Alessandro M. Rizzi
  19. Daniel G. Chen
  20. Kelsey Furiya
  21. Nick Horst
  22. Tianzi Zhang
  23. Phung Le
  24. Kelly McKenna
  25. Shannon K. Oda
  26. Anthony Rongvaux
  27. Phillip D. Greenberg
  28. Thomas M. Schmitt
  29. Aude G. Chapuis
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  1. Version published to 10.1038/s41467-025-67446-5
  2. Version published to 10.21203/rs.3.rs-5939098/v1 on Research Square