Bibliometric and Visual Analysis on Coronary Artery Calcification from 2003 to 2024

The study utilized the Web of Science core collection database to retrieve all CAC-related publications from January 1, 2003, to August 31, 2024. Microsoft Excel was used to analyze publication volume, trends, and journal publication volume. VOSviewer software was applied to visualize the collaboration network among authors, while Citespace software was used for analyzing institutions, keywords co-occurrence, keywords clustering, and keywords burst detection. The study collected 3,069 publications on CAC from the Web of Science database between 2003 and 2024. Budoff, Matthew J. was identified as the most prolific author, with 161 articles. Nine of the top ten institutions in terms of publication volume located in the U.S., indicating that the U.S. is leading in this research area. Current research on CAC focuses on quantitative assessment and its association with the progression of cardiovascular diseases, particularly studies related to coronary artery disease and atherosclerosis, which have emerged as research hotspots in recent years. Research on coronary artery calcification has centered on early diagnosis and risk assessment, especially through quantification of calcification scores using CT imaging to predict cardiovascular event risk. Furthermore, there is a focus on the biological mechanisms of calcification and its relationship with atherosclerosis.