Association Between Zinc Dietary Intake And Constipation: A Population-based Study

Background : Several studies have proposed a connection between the beginning of constipation and the consumption of dietary micronutrients. However, little study has been done on the possible connection between constipation and ZINC. This study sought to ascertain whether there was a relationship between chronic constipation and dietary zinc intake in adult National Health and Nutrition Examination Survey (NHANES) participants. Method : Data from the 2009–2010 NHANES health and nutrition survey were used in the study. 24-hour dietary recalls were used to collect dietary information from respondents. Numerous statistical techniques, including interaction testing, subgroup analysis, and curve fitting studies, were used to examine the connection between dietary zinc intake and chronic constipation. Result: Out of the 3,643 individuals in this research, 270 (7.41%) had a chronic constipation diagnosis. Increasing dietary zinc intake was associated with a decreased incidence of constipation (OR=0.78, 95% CI: 0.68-0.89), with significance at p<0.05, according to a fully adjusted multiple logistic regression analysis. as several factors were taken into consideration, the third tertile's odds ratio and 95% CI were 0.85 (0.74, 0.98), with statistical significance at p<0.05, as compared to the reference group (first tertile). Furthermore, subgroup analysis showed no correlation in most groups, while a certain negative correlation was found in males and alcohol drinkers, particularly in males and alcohol drinkers. In conclusion, this study found a negative association between zinc consumption and the prevalence of chronic constipation. In-depth prospective studies are needed to fully examine the long-term effects of zinc on chronic constipation.