Identification and Genetic Evolution Analysis of Muscovy Duck Parvovirus in Guangdong Province

In this study, we analyzed 137 liver samples collected from deceased Muscovy ducks in Guangdong, China, between 2020 and 2023. The GD2407 strain was isolated from these samples. Genomic analysis revealed that the complete genome of GD2407 is 5067 bp in length, encoding both non-structural (NS) and structural proteins (VP). Identity analysis demonstrated that GD2407 shares 99.9% homology with the GDZJ1901 strain. Recombination analysis indicated that GD2407 originated from a recombination event between Muscovy duck parvovirus (MDPV) and goose parvovirus (GPV). Genetic evolution analysis showed that GD2407 is genetically closely related to GDZJ1901 but distinct from the pre-2020 prevalent GD201911 strain. These findings suggest that the circulation of MDPV in this region may contribute to illness and mortality in ducks.