PFDB: Polyphenol Family Database

Polyphenols and their derivatives are pivotal bioactive compounds in the plant kingdom and are known for their diverse physiological effects and significant contributions to human health. Understanding their biosynthetic pathways is crucial for exploring their roles in plant defense, environmental adaptation, and human nutrition. This study introduces the Polyphenol Family Database (PFDB, url: http://pfdb.ynau.edu.cn), a comprehensive and user-friendly resource designed to facilitate the exploration and analysis of these compounds. PFDB consolidates information on 64 enzymes across 284 species, offering a comprehensive view of their biosynthetic pathways and evolutionary relationships. The database features an intuitive structure with six main sections, including detailed pathway maps and a species-enzyme detail page that provides in-depth information on specific enzymes and their genetic and phylogenetic context. This integration of biochemical and genetic data makes PFDB a valuable tool for researchers in plant biology, biochemistry, and nutrition, facilitating advanced research and comparative analyses in the field. URL: http://pfdb.ynau.edu.cn