Trajectory of lung ultrasound scores in preterm infants at risk for bronchopulmonary dysplasia
Discuss this preprint
Start a discussion What are Sciety discussions?Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
Objective
To quantify the trajectory of lung ultrasound scores (LUSSc) and estimate their association on inpatient respiratory trajectories in preterm infants with potentially evolving bronchopulmonary dysplasia (BPD)
Study design
We measured LUSSc prospectively in infants <32 weeks’ gestation weekly from 2 weeks of life through 44 weeks’ post-menstrual age (PMA) or discharge. The primary outcome was the age, in PMA, to achieve liberation of respiratory support (LRS) defined as room air or < 1 L/min (F i O 2 = 100%).
Result
In 16 infants, 10 patients had Grade 2–3 BPD, and LUSSc declined over time. The median age to achieve LRS was 42 weeks’ PMA (33.6, 47.9). Using the maximum LUSSc each infant had between 30 and 32 weeks’ PMA, each 1-point increase in the LUSSc was independently associated with a 9-day increase in the age to achieve LRS.
Conclusion
LUSSc may serve as a diagnostic marker for inpatient respiratory trajectories of preterm infants with evolving BPD.
