Retrospective Evaluation of Demographic, Clinical, Laboratory Findings and Inflammatory Biomarkers of Patients Followed with the Diagnosis of Serum Sickness-Like Reaction

Objectives In the present study, the purpose was to examine whether there are any changes in these hematological parameters and their prognostic significance in patients diagnosed with SSLR and followed and treated in our clinic. Methods The files of 122 patients who were hospitalized and followed up with a diagnosis of SSLR in the Pediatric Healthcare and Diseases Clinic between September 2016 and December 2021 were examined retrospectively. Results A total of 64 (52.5%) of the patients were male, 58 (47.5%) were female. The age distribution of the patients varied between 14 months and 213 months. When the clinical findings of the patients who were included in the study were examined. Statistically significant differences were detected in the Neutrophil Count, Lymphocyte Count, NLR, PLR, RLR, AST/ALT Ratio, SII, and AST/PLT ratios of the patients compared to the control group. According to the ROC analysis results of the present study, it was found that NLR, PLR, RLR, RLR, and SII values were statistically high in diagnosis. Conclusions NLR and PLR values were elevated in SSLR patients, showing that these parameters can be used as important inflammation markers in the diagnosis and follow-up of the disease.