Misdiagnosis of the Polymorphous Low-Grade Neuroepithelial Tumor of the Young as Ganglioglioma,A Case Report

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Abstract

Background PLNTY traditionally manifests as an epileptogenic subtype, posing challenges in differential diagnosis. The low incidence of PLNTY and the similarity of its clinical presentation and imaging features with other types of neuroepithelial tumors have made it important to diagnose PLNTY accurately. Case presentation We report here an unusual case of a PLNTY in a 14-year-old girl who was admitted to the hospital with acute headache, nausea, and vomiting, initially misdiagnosed as ganglioglioma on imaging, and then diagnosed as pleomorphic low-grade neuroepithelial tumor (PLNTY) on surgical and pathological analyses. The patient did not present with typical epileptic symptoms, PLNTY is a rare adolescent low-grade brain tumor with imaging manifestations similar to those of other neuroepithelial tumors, which is easy to lead to misdiagnosis. Conclusion PLNTY is a class of adolescent low-grade neuroepithelial tumors with good prognosis. Definitive diagnosis of PLNTY is of great significance to avoid over-treatment and improve the quality of survival in pediatric and adolescent patients.

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