Anti-GluK2 Antibody-Positive Autoimmune Encephalitis Concurrent with Multiple Myeloma: A Case Report
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Background It is the first reported instance of GluK2 antibody-associated autoimmune encephalitis with involuntary movement. Case presentation A 60-year-old woman who experienced involuntary movements of her lower limbs and facial muscle for two years，sometimes accompanied with hysterical shouting. Ater the treatment for multiple myeloma, bone marrow examinations showed that the proportion of myeloma cells have a sustained decline which indicated the treatment worked, meanwhile, all the symptoms disappeared and the concentrations of anti-GluK2 antibody IgG decreased sharply. Conclusions This case revealed that the involuntary movements and the emotion is a new phenotype of Anti-GluK2 Antibody-Positive Autoimmune Encephalitis.
