A Comparison Between the Bowel Ultrasound Score and International Bowel Ultrasound Segmental Activity Score Based on Ileocolonoscopy in Patients with Crohn’s Disease

Background and Aim We aimed to compare two main existing scores, Bowel Ultrasound Score (BUSS) and International Bowel Ultrasound Segmental Activity Score (IBUS-SAS) to predict simplified endoscopic activity score for CD (SES-CD). Methods A cross-sectional study was performed to evaluate the disease activity in CD patients with ileal involvement between November 2019 and February 2024. Remission for CD was accepted for SES-CD ≤2. Results Total 56 adult patients with CD (Male; 38, 67.9%, Median age; 40.5 years) were included in the study, the median duration of the disease was 8.4 years. The cut-off value for BUSS to determine endoscopic remission was 3.9, while the cut-off value for IBUS-SAS to establish endoscopic remission was 24.4. BUSS and SES-CD had a strong positive correlation (p<0.001), BUSS and IBUS-SAS had a high positive correlation (p<0.001), and BUSS and CRP had a slightly positive correlation (p<0.001). Conclusion In this study, we found that the most accurate cut-off value for BUSS was 3.9 and the most accurate cut-off value for IBUS-SAS was 24.4 in CD patients with endoscopic remission group. Furthermore, we have confirmed that both BUSS and IBUS-SAS significantly correlate with endoscopic activity in a real-world cohort.