Associations between different triglyceride glucose index-related obesity indices and eating disorders: results from NHANES 2005–2018

Background This research aimed to determine the possible links between obesity measures related to the triglyceride glucose (TyG) index and the prevalence of eating disorders (ED) for the United States residents. Methods This observational investigation analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2005–2018. It assessed the relationship of the TyG index, TyG combined with waist circumference (TyG-WC), or TyG combined with body mass index (TyG-BMI) with ED. The analysis employed a multivariable regression model, stratified analyses, and a ROC curve assessment. Results This research included a total of 10,324 adults. In the comprehensive analysis model, the TyG, TyG-BMI, along with TyG-WC all had a significant positive correlation with ED. The adjusted graphical representations revealed a rising trend in the association of TyG-BMI index with ED. Subgroup analyses indicated that individuals with hypertension exhibited even stronger positive associations between these indices and ED. The areas under the curve (AUC) values indicates the value for TyG-related indicators in predicting ED. Conclusions The research uncovered a significant and enduring connection between obesity measures related to the TyG-related index and ED, indicating a robust association of increased insulin resistance with the probability of ED among the U.S. population.