Effect of the defocus ring area after orthokeratology lens wear on the progression of adolescent myopia Running title: The defocus ring area after OK lens wear and myopia control
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This article is not in any list yet, why not save it to one of your lists.Abstract
Objective Orthokeratology (OK) lenses are one of the most effective optical treatments for myopia control. Herein, this study investigated the effect of the defocus ring area after OK lens wear on the progression of myopia in adolescents. Methods A total of 180 myopic adolescents were randomized into control (wearing frame glasses) and OK lens groups (90 cases per group). The diopter, ocular axial length, and visual quality of participants were recorded. The Spearman's correlation, multivariate logistic regression, and ROC analyses were performed to assess effect of the defocus ring area on the progression of myopia (growth of the ocular axis and diopter) and its predictive value for the progression of myopia. Results The increase in the growth of ocular axial length and diopter was significantly slowed after 1 year of lens wear. Additionally, the visual quality was not affected after 1 year of OK lens wear. The defocus ring area was positively correlated with the growth of the ocular axis and the diopter after 1 year of OK lens wear. The increased defocus ring area after OK lens wear was an independent risk factor for poor myopia control. The defocus ring area could aid in predicting myopia progression in adolescents (cutoff value, 22.05) with high AUC, sensitivity, and specificity. Conclusion The defocus ring area after OK lens wear is an independent risk factor for myopia progression in adolescents and can assist in predicting myopia progression after 1 year of lens wear.