Global trends and focuses of Integrins in Colorectal Cancer: a bibliometric analysis and visualization from 2007 to 2023

Colorectal cancer is one of the most common tumors of the digestive system; however, current treatment methods still have certain limitations. In recent years, researchers have found that integrins play a crucial role in colorectal cancer, making them a hot topic in research. To gain a better understanding of the current status and trends of integrins in colorectal cancer research, this study conducted a bibliometric analysis for the first time to assess the development of integrin-related research in colorectal cancer. The study selected the core dataset from the Web of Science database and included relevant research on integrins and colorectal cancer published between 2007 and 2023. The CiteSpace, VoSviewer, and Bibliometrix R packages were utilized for analyzing the aspects of country/region, authors, institutions, journals, references, and keywords. The analysis revealed steady growth in research on integrins and colorectal cancer over the past 16 years, with a total of 1,339 articles published by 61 countries. Among them, China has the highest number of publications, followed by the United States. The most frequently cited journal is Cancer Research , followed by the Journal of Biological Chemistry and Oncogene . In conclusion, bibliometric analysis provided a comprehensive visualization of the current status and trends in research on integrins in colorectal cancer. These analytical results not only offer valuable insights for researchers but also provide useful information for decision-makers in the scientific and medical communities. This, in turn, can facilitate the improvement and development of treatment methods for colorectal cancer.