Chronic endometritis and fertility: still a debatable issue

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Abstract

Purpose: We conducted this study to help elucidate the clinical relevance of CE with fertility. Methods: Prospective cohort study including 60 patients undergoing hysteroscopy for various indications were triaged into three arms: patients with a history of implantation failure in IVF treatment constructed the first arm (#25), second arm included patients with a history of recurrent pregnancy loss (#20) and the third group confined patients undergoing H/S for other indications (#15). Endometrial sampling was performed in all cases prior to starting the H/S procedure. Results: Baseline characteristics, demographic variables and percentage of history of healthy deliveries were similar for the three groups. Twenty six (43%) patients were diagnosed with CE based on histopathologic assessment, and endometrial culture results were positive in only two (3.3%) cases. We found no difference in the incidence of CE among three groups. Conclusion: CE may be among the probable reasons for reproductive disorders but strenous investigations should be reserved in limited cases whereas more probable reasons have been excluded.

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